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Molecular determinants of anti-EGFR sensitivity and resistance in metastatic colorectal cancer
Since 2004, the clinical impact of monoclonal antibodies (mAbs) targeting the epidermal growth factor receptor (EGFR) on patients with metastatic colorectal cancer (MCRC) has been clearly established. The combination of these biological agents with conventional chemotherapy has led to a significant...
Autores principales: | Di Fiore, F, Sesboüé, R, Michel, P, Sabourin, J C, Frebourg, T |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008616/ https://www.ncbi.nlm.nih.gov/pubmed/21139621 http://dx.doi.org/10.1038/sj.bjc.6606008 |
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