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Paintomics: a web based tool for the joint visualization of transcriptomics and metabolomics data
Motivation: The development of the omics technologies such as transcriptomics, proteomics and metabolomics has made possible the realization of systems biology studies where biological systems are interrogated at different levels of biochemical activity (gene expression, protein activity and/or meta...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008637/ https://www.ncbi.nlm.nih.gov/pubmed/21098431 http://dx.doi.org/10.1093/bioinformatics/btq594 |
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author | García-Alcalde, Fernando García-López, Federico Dopazo, Joaquín Conesa, Ana |
author_facet | García-Alcalde, Fernando García-López, Federico Dopazo, Joaquín Conesa, Ana |
author_sort | García-Alcalde, Fernando |
collection | PubMed |
description | Motivation: The development of the omics technologies such as transcriptomics, proteomics and metabolomics has made possible the realization of systems biology studies where biological systems are interrogated at different levels of biochemical activity (gene expression, protein activity and/or metabolite concentration). An effective approach to the analysis of these complex datasets is the joined visualization of the disparate biomolecular data on the framework of known biological pathways. Results: We have developed the Paintomics web server as an easy-to-use bioinformatics resource that facilitates the integrated visual analysis of experiments where transcriptomics and metabolomics data have been measured on different conditions for the same samples. Basically, Paintomics takes complete transcriptomics and metabolomics datasets, together with lists of significant gene or metabolite changes, and paints this information on KEGG pathway maps. Availability: Paintomics is freely available at http://www.paintomics.org. Contact: aconesa@cipf.es |
format | Text |
id | pubmed-3008637 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-30086372010-12-29 Paintomics: a web based tool for the joint visualization of transcriptomics and metabolomics data García-Alcalde, Fernando García-López, Federico Dopazo, Joaquín Conesa, Ana Bioinformatics Applications Note Motivation: The development of the omics technologies such as transcriptomics, proteomics and metabolomics has made possible the realization of systems biology studies where biological systems are interrogated at different levels of biochemical activity (gene expression, protein activity and/or metabolite concentration). An effective approach to the analysis of these complex datasets is the joined visualization of the disparate biomolecular data on the framework of known biological pathways. Results: We have developed the Paintomics web server as an easy-to-use bioinformatics resource that facilitates the integrated visual analysis of experiments where transcriptomics and metabolomics data have been measured on different conditions for the same samples. Basically, Paintomics takes complete transcriptomics and metabolomics datasets, together with lists of significant gene or metabolite changes, and paints this information on KEGG pathway maps. Availability: Paintomics is freely available at http://www.paintomics.org. Contact: aconesa@cipf.es Oxford University Press 2011-01-01 2010-11-23 /pmc/articles/PMC3008637/ /pubmed/21098431 http://dx.doi.org/10.1093/bioinformatics/btq594 Text en © The Author(s) 2010. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/2.0/uk/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Applications Note García-Alcalde, Fernando García-López, Federico Dopazo, Joaquín Conesa, Ana Paintomics: a web based tool for the joint visualization of transcriptomics and metabolomics data |
title | Paintomics: a web based tool for the joint visualization of transcriptomics and metabolomics data |
title_full | Paintomics: a web based tool for the joint visualization of transcriptomics and metabolomics data |
title_fullStr | Paintomics: a web based tool for the joint visualization of transcriptomics and metabolomics data |
title_full_unstemmed | Paintomics: a web based tool for the joint visualization of transcriptomics and metabolomics data |
title_short | Paintomics: a web based tool for the joint visualization of transcriptomics and metabolomics data |
title_sort | paintomics: a web based tool for the joint visualization of transcriptomics and metabolomics data |
topic | Applications Note |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008637/ https://www.ncbi.nlm.nih.gov/pubmed/21098431 http://dx.doi.org/10.1093/bioinformatics/btq594 |
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