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Paintomics: a web based tool for the joint visualization of transcriptomics and metabolomics data

Motivation: The development of the omics technologies such as transcriptomics, proteomics and metabolomics has made possible the realization of systems biology studies where biological systems are interrogated at different levels of biochemical activity (gene expression, protein activity and/or meta...

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Detalles Bibliográficos
Autores principales: García-Alcalde, Fernando, García-López, Federico, Dopazo, Joaquín, Conesa, Ana
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008637/
https://www.ncbi.nlm.nih.gov/pubmed/21098431
http://dx.doi.org/10.1093/bioinformatics/btq594
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author García-Alcalde, Fernando
García-López, Federico
Dopazo, Joaquín
Conesa, Ana
author_facet García-Alcalde, Fernando
García-López, Federico
Dopazo, Joaquín
Conesa, Ana
author_sort García-Alcalde, Fernando
collection PubMed
description Motivation: The development of the omics technologies such as transcriptomics, proteomics and metabolomics has made possible the realization of systems biology studies where biological systems are interrogated at different levels of biochemical activity (gene expression, protein activity and/or metabolite concentration). An effective approach to the analysis of these complex datasets is the joined visualization of the disparate biomolecular data on the framework of known biological pathways. Results: We have developed the Paintomics web server as an easy-to-use bioinformatics resource that facilitates the integrated visual analysis of experiments where transcriptomics and metabolomics data have been measured on different conditions for the same samples. Basically, Paintomics takes complete transcriptomics and metabolomics datasets, together with lists of significant gene or metabolite changes, and paints this information on KEGG pathway maps. Availability: Paintomics is freely available at http://www.paintomics.org. Contact: aconesa@cipf.es
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spelling pubmed-30086372010-12-29 Paintomics: a web based tool for the joint visualization of transcriptomics and metabolomics data García-Alcalde, Fernando García-López, Federico Dopazo, Joaquín Conesa, Ana Bioinformatics Applications Note Motivation: The development of the omics technologies such as transcriptomics, proteomics and metabolomics has made possible the realization of systems biology studies where biological systems are interrogated at different levels of biochemical activity (gene expression, protein activity and/or metabolite concentration). An effective approach to the analysis of these complex datasets is the joined visualization of the disparate biomolecular data on the framework of known biological pathways. Results: We have developed the Paintomics web server as an easy-to-use bioinformatics resource that facilitates the integrated visual analysis of experiments where transcriptomics and metabolomics data have been measured on different conditions for the same samples. Basically, Paintomics takes complete transcriptomics and metabolomics datasets, together with lists of significant gene or metabolite changes, and paints this information on KEGG pathway maps. Availability: Paintomics is freely available at http://www.paintomics.org. Contact: aconesa@cipf.es Oxford University Press 2011-01-01 2010-11-23 /pmc/articles/PMC3008637/ /pubmed/21098431 http://dx.doi.org/10.1093/bioinformatics/btq594 Text en © The Author(s) 2010. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/2.0/uk/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Applications Note
García-Alcalde, Fernando
García-López, Federico
Dopazo, Joaquín
Conesa, Ana
Paintomics: a web based tool for the joint visualization of transcriptomics and metabolomics data
title Paintomics: a web based tool for the joint visualization of transcriptomics and metabolomics data
title_full Paintomics: a web based tool for the joint visualization of transcriptomics and metabolomics data
title_fullStr Paintomics: a web based tool for the joint visualization of transcriptomics and metabolomics data
title_full_unstemmed Paintomics: a web based tool for the joint visualization of transcriptomics and metabolomics data
title_short Paintomics: a web based tool for the joint visualization of transcriptomics and metabolomics data
title_sort paintomics: a web based tool for the joint visualization of transcriptomics and metabolomics data
topic Applications Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008637/
https://www.ncbi.nlm.nih.gov/pubmed/21098431
http://dx.doi.org/10.1093/bioinformatics/btq594
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