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Automated construction and testing of multi-locus gene–gene associations
Summary: It has been argued that the missing heritability in common diseases may be in part due to rare variants and gene–gene effects. Haplotype analyses provide more power for rare variants and joint analyses across genes can address multi-gene effects. Currently, methods are lacking to perform jo...
Autores principales: | Abo, Ryan, Knight, Stacey, Thomas, Alun, Camp, Nicola J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008644/ https://www.ncbi.nlm.nih.gov/pubmed/21076150 http://dx.doi.org/10.1093/bioinformatics/btq616 |
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