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Zebrafish models of the immune response: taking it on the ChIn
The zebrafish is proving to be an extremely versatile new experimental model for unraveling the mysteries of innate immunity and has considerable promise as a system for the identification of novel modulators of this crucial biological process. A rate-limiting factor, however, is the mechanical stim...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008691/ https://www.ncbi.nlm.nih.gov/pubmed/21176245 http://dx.doi.org/10.1186/1741-7007-8-148 |
| _version_ | 1782194535794737152 |
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| author | Renshaw, Stephen A Ingham, Philip W |
| author_facet | Renshaw, Stephen A Ingham, Philip W |
| author_sort | Renshaw, Stephen A |
| collection | PubMed |
| description | The zebrafish is proving to be an extremely versatile new experimental model for unraveling the mysteries of innate immunity and has considerable promise as a system for the identification of novel modulators of this crucial biological process. A rate-limiting factor, however, is the mechanical stimulus required to induce the inflammatory response. A new chemically induced inflammation assay ('ChIn' assay) published in BMC Biology obviates this requirement and seems set to accelerate progress in the field. |
| format | Text |
| id | pubmed-3008691 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2010 |
| publisher | BioMed Central |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-30086912010-12-23 Zebrafish models of the immune response: taking it on the ChIn Renshaw, Stephen A Ingham, Philip W BMC Biol Commentary The zebrafish is proving to be an extremely versatile new experimental model for unraveling the mysteries of innate immunity and has considerable promise as a system for the identification of novel modulators of this crucial biological process. A rate-limiting factor, however, is the mechanical stimulus required to induce the inflammatory response. A new chemically induced inflammation assay ('ChIn' assay) published in BMC Biology obviates this requirement and seems set to accelerate progress in the field. BioMed Central 2010-12-22 /pmc/articles/PMC3008691/ /pubmed/21176245 http://dx.doi.org/10.1186/1741-7007-8-148 Text en Copyright ©2010 Renshaw and Ingham; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| spellingShingle | Commentary Renshaw, Stephen A Ingham, Philip W Zebrafish models of the immune response: taking it on the ChIn |
| title | Zebrafish models of the immune response: taking it on the ChIn |
| title_full | Zebrafish models of the immune response: taking it on the ChIn |
| title_fullStr | Zebrafish models of the immune response: taking it on the ChIn |
| title_full_unstemmed | Zebrafish models of the immune response: taking it on the ChIn |
| title_short | Zebrafish models of the immune response: taking it on the ChIn |
| title_sort | zebrafish models of the immune response: taking it on the chin |
| topic | Commentary |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008691/ https://www.ncbi.nlm.nih.gov/pubmed/21176245 http://dx.doi.org/10.1186/1741-7007-8-148 |
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