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The Receptor Tyrosine Kinase FGFR4 Negatively Regulates NF-kappaB Signaling

BACKGROUND: NFκB signaling is of paramount importance in the regulation of apoptosis, proliferation, and inflammatory responses during human development and homeostasis, as well as in many human cancers. Receptor Tyrosine Kinases (RTKs), including the Fibroblast Growth Factor Receptors (FGFRs) are a...

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Detalles Bibliográficos
Autores principales: Drafahl, Kristine A., McAndrew, Christopher W., Meyer, April N., Haas, Martin, Donoghue, Daniel J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008709/
https://www.ncbi.nlm.nih.gov/pubmed/21203561
http://dx.doi.org/10.1371/journal.pone.0014412