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Structural and aggregation behavior of the human γD-crystallin mutant E107A, associated with congenital nuclear cataract
PURPOSE: To analyze the conformational features and aggregation properties of the mutant protein E107A human γD-crystallin (HGDC), associated with congenital nuclear cataract. METHODS: cDNAs of wild type and E107A mutant were cloned and expressed in BL21 (DE3) pLysS cells and the proteins isolated a...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Molecular Vision
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008718/ https://www.ncbi.nlm.nih.gov/pubmed/21197114 |