High-Definition Mapping of Retroviral Integration Sites Defines the Fate of Allogeneic T Cells After Donor Lymphocyte Infusion

The infusion of donor lymphocytes transduced with a retroviral vector expressing the HSV-TK suicide gene in patients undergoing hematopoietic stem cell transplantation for leukemia/lymphoma promotes immune reconstitution and prevents infections and graft-versus-host disease. Analysis of the clonal d...

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Detalles Bibliográficos
Autores principales: Cattoglio, Claudia, Maruggi, Giulietta, Bartholomae, Cynthia, Malani, Nirav, Pellin, Danilo, Cocchiarella, Fabienne, Magnani, Zulma, Ciceri, Fabio, Ambrosi, Alessandro, von Kalle, Christof, Bushman, Frederic D., Bonini, Chiara, Schmidt, Manfred, Mavilio, Fulvio, Recchia, Alessandra
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008730/
https://www.ncbi.nlm.nih.gov/pubmed/21203516
http://dx.doi.org/10.1371/journal.pone.0015688

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