Polyfunctional T-Cell Responses Are Disrupted by the Ovarian Cancer Ascites Environment and Only Partially Restored by Clinically Relevant Cytokines

BACKGROUND: Host T-cell responses are associated with favorable outcomes in epithelial ovarian cancer (EOC), but it remains unclear how best to promote these responses in patients. Toward this goal, we evaluated a panel of clinically relevant cytokines for the ability to enhance multiple T-cell effe...

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Detalles Bibliográficos
Autores principales: Tran, Eric, Nielsen, Julie S., Wick, Darin A., Ng, Alvin V., Johnson, Lisa D. S., Nesslinger, Nancy J., McMurtrie, Elissa, Webb, John R., Nelson, Brad H.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008736/
https://www.ncbi.nlm.nih.gov/pubmed/21203522
http://dx.doi.org/10.1371/journal.pone.0015625

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