PENUFLURIDOL IN THE TREATMENT OF SCHIZOPHRENICS

Twenty nine chronic schizophrenics maintained on trifluperazinc treatment were included in the trial trifluperazinc was discontinued till relapse occured. Standard injectable trifluperazinc was reinstituted for 10 days. This was replaced by weekly dose of 20-40 mg penfluridol orally for a period of...

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Detalles Bibliográficos
Autor principal: Sharma, S. D.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 1988
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008798/
https://www.ncbi.nlm.nih.gov/pubmed/21927345
Descripción
Sumario:Twenty nine chronic schizophrenics maintained on trifluperazinc treatment were included in the trial trifluperazinc was discontinued till relapse occured. Standard injectable trifluperazinc was reinstituted for 10 days. This was replaced by weekly dose of 20-40 mg penfluridol orally for a period of d months. Assessment was done monthly and side effects were monitored. At the end of 6 months, 28 patients not only maintained but improved in the psychiatric status. The trial has confirmed that penfluridol is a safe and effective drug which would be suitable for maintenance therapy in schizophrenic patients.

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