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pH-dependent localization of Btn1p in the yeast model for Batten disease
Btn1p the yeast homolog of human CLN3, which is associated with juvenile Batten disease has been implicated in several cellular pathways. Yeast cells lacking BTN1 are unable to couple ATP hydrolysis and proton pumping activities by the vacuolar ATPase (V-ATPase). In this work, we demonstrate that ch...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Limited
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008966/ https://www.ncbi.nlm.nih.gov/pubmed/20959629 http://dx.doi.org/10.1242/dmm.006114 |