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N-(2-Chloro­pyrimidin-4-yl)-N,2-di­methyl-2H-indazol-6-amine

In the title compound, C(13)H(12)ClN(5), which is a derivative of the anti­tumor agent pazopanib {systematic name: 5-[[4-[(2,3-di­methyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzolsulfonamide}, the indazole and pyrim­idine fragments form a dihedral angle of 62.63 (5)°. In the cr...

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Detalles Bibliográficos
Autores principales: Qi, Hao-Fei, Liu, Bing-Ni, Liu, Mo, Liu, Deng-Ke
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009102/
https://www.ncbi.nlm.nih.gov/pubmed/21589123
http://dx.doi.org/10.1107/S1600536810042753
Descripción
Sumario:In the title compound, C(13)H(12)ClN(5), which is a derivative of the anti­tumor agent pazopanib {systematic name: 5-[[4-[(2,3-di­methyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzolsulfonamide}, the indazole and pyrim­idine fragments form a dihedral angle of 62.63 (5)°. In the crystal, pairs of mol­ecules related by twofold rotational symmetry are linked into dimers through π–π inter­actions between the indazole ring systems [centroid–centroid distance = 3.720 (2) Å]. Weak inter­molecular C—H⋯N hydrogen bonds further assemble these dimers into columns propagated in [001].