2-Fluoro-l-histidine

The title compound, C(6)H(8)FN(3)O(2), an analog of histidine, shows a reduced side-chain pK(a) (ca 1). The title structure exhibits a shortening of the bond between the proximal ring N atom and the F-substituted ring C atom, indicating an increase in π-bond character due to an inductive effect of f...

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Detalles Bibliográficos
Autores principales: Andra, Kiran K., Bullinger, John C., Bann, James G., Eichhorn, David M.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009228/
https://www.ncbi.nlm.nih.gov/pubmed/21588926
http://dx.doi.org/10.1107/S1600536810038663
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author Andra, Kiran K.
Bullinger, John C.
Bann, James G.
Eichhorn, David M.
author_facet Andra, Kiran K.
Bullinger, John C.
Bann, James G.
Eichhorn, David M.
author_sort Andra, Kiran K.
collection PubMed
description The title compound, C(6)H(8)FN(3)O(2), an analog of histidine, shows a reduced side-chain pK(a) (ca 1). The title structure exhibits a shortening of the bond between the proximal ring N atom and the F-substituted ring C atom, indicating an increase in π-bond character due to an inductive effect of fluorine.
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spelling pubmed-30092282010-12-30 2-Fluoro-l-histidine Andra, Kiran K. Bullinger, John C. Bann, James G. Eichhorn, David M. Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(6)H(8)FN(3)O(2), an analog of histidine, shows a reduced side-chain pK(a) (ca 1). The title structure exhibits a shortening of the bond between the proximal ring N atom and the F-substituted ring C atom, indicating an increase in π-bond character due to an inductive effect of fluorine. International Union of Crystallography 2010-10-02 /pmc/articles/PMC3009228/ /pubmed/21588926 http://dx.doi.org/10.1107/S1600536810038663 Text en © Andra et al. 2010 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Andra, Kiran K.
Bullinger, John C.
Bann, James G.
Eichhorn, David M.
2-Fluoro-l-histidine
title 2-Fluoro-l-histidine
title_full 2-Fluoro-l-histidine
title_fullStr 2-Fluoro-l-histidine
title_full_unstemmed 2-Fluoro-l-histidine
title_short 2-Fluoro-l-histidine
title_sort 2-fluoro-l-histidine
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009228/
https://www.ncbi.nlm.nih.gov/pubmed/21588926
http://dx.doi.org/10.1107/S1600536810038663
work_keys_str_mv AT andrakirank 2fluorolhistidine
AT bullingerjohnc 2fluorolhistidine
AT bannjamesg 2fluorolhistidine
AT eichhorndavidm 2fluorolhistidine

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