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[2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]methanol
The title compound, C(19)H(16)FNO, crystallizes with two independent molecules in the asymmetric unit. In the two molecules, the dihedral angles between the benzene and quinoline rings are 72.6 (5) and 76.2 (5)°, between the cyclopropane and quinoline rings they are 65.2 (5) and 66.0 (5)°, and be...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009308/ https://www.ncbi.nlm.nih.gov/pubmed/21589152 http://dx.doi.org/10.1107/S1600536810043588 |
Sumario: | The title compound, C(19)H(16)FNO, crystallizes with two independent molecules in the asymmetric unit. In the two molecules, the dihedral angles between the benzene and quinoline rings are 72.6 (5) and 76.2 (5)°, between the cyclopropane and quinoline rings they are 65.2 (5) and 66.0 (5)°, and between the benzene and cyclopropane rings they are 25.9 (5) and 33.9 (5)°. There are intermolecular O—H⋯O, O—H⋯N and C—H⋯O hydrogen bonds, as well as intramolecular C—H⋯O hydrogen bonds, which may be effective in stabilizing the crystal structure. |
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