[2-Cyclo­propyl-4-(4-fluoro­phenyl)quinolin-3-yl]methanol

The title compound, C(19)H(16)FNO, crystallizes with two independent mol­ecules in the asymmetric unit. In the two mol­ecules, the dihedral angles between the benzene and quinoline rings are 72.6 (5) and 76.2 (5)°, between the cyclo­propane and quinoline rings they are 65.2 (5) and 66.0 (5)°, and be...

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Detalles Bibliográficos
Autores principales: Sun, Hongshun, Xu, Hong, Li, Yu-Long
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009308/
https://www.ncbi.nlm.nih.gov/pubmed/21589152
http://dx.doi.org/10.1107/S1600536810043588
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author Sun, Hongshun
Xu, Hong
Li, Yu-Long
author_facet Sun, Hongshun
Xu, Hong
Li, Yu-Long
author_sort Sun, Hongshun
collection PubMed
description The title compound, C(19)H(16)FNO, crystallizes with two independent mol­ecules in the asymmetric unit. In the two mol­ecules, the dihedral angles between the benzene and quinoline rings are 72.6 (5) and 76.2 (5)°, between the cyclo­propane and quinoline rings they are 65.2 (5) and 66.0 (5)°, and between the benzene and cyclo­propane rings they are 25.9 (5) and 33.9 (5)°. There are inter­molecular O—H⋯O, O—H⋯N and C—H⋯O hydrogen bonds, as well as intra­molecular C—H⋯O hydrogen bonds, which may be effective in stabilizing the crystal structure.
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spelling pubmed-30093082010-12-30 [2-Cyclo­propyl-4-(4-fluoro­phenyl)quinolin-3-yl]methanol Sun, Hongshun Xu, Hong Li, Yu-Long Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(19)H(16)FNO, crystallizes with two independent mol­ecules in the asymmetric unit. In the two mol­ecules, the dihedral angles between the benzene and quinoline rings are 72.6 (5) and 76.2 (5)°, between the cyclo­propane and quinoline rings they are 65.2 (5) and 66.0 (5)°, and between the benzene and cyclo­propane rings they are 25.9 (5) and 33.9 (5)°. There are inter­molecular O—H⋯O, O—H⋯N and C—H⋯O hydrogen bonds, as well as intra­molecular C—H⋯O hydrogen bonds, which may be effective in stabilizing the crystal structure. International Union of Crystallography 2010-10-31 /pmc/articles/PMC3009308/ /pubmed/21589152 http://dx.doi.org/10.1107/S1600536810043588 Text en © Sun et al. 2010 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Sun, Hongshun
Xu, Hong
Li, Yu-Long
[2-Cyclo­propyl-4-(4-fluoro­phenyl)quinolin-3-yl]methanol
title [2-Cyclo­propyl-4-(4-fluoro­phenyl)quinolin-3-yl]methanol
title_full [2-Cyclo­propyl-4-(4-fluoro­phenyl)quinolin-3-yl]methanol
title_fullStr [2-Cyclo­propyl-4-(4-fluoro­phenyl)quinolin-3-yl]methanol
title_full_unstemmed [2-Cyclo­propyl-4-(4-fluoro­phenyl)quinolin-3-yl]methanol
title_short [2-Cyclo­propyl-4-(4-fluoro­phenyl)quinolin-3-yl]methanol
title_sort [2-cyclo­propyl-4-(4-fluoro­phenyl)quinolin-3-yl]methanol
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009308/
https://www.ncbi.nlm.nih.gov/pubmed/21589152
http://dx.doi.org/10.1107/S1600536810043588
work_keys_str_mv AT sunhongshun 2cyclopropyl44fluorophenylquinolin3ylmethanol
AT xuhong 2cyclopropyl44fluorophenylquinolin3ylmethanol
AT liyulong 2cyclopropyl44fluorophenylquinolin3ylmethanol

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