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A hybrid approach to protein folding problem integrating constraint programming with local search

BACKGROUND: The protein folding problem remains one of the most challenging open problems in computational biology. Simplified models in terms of lattice structure and energy function have been proposed to ease the computational hardness of this optimization problem. Heuristic search algorithms and...

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Detalles Bibliográficos
Autores principales: Ullah, Abu Dayem, Steinhöfel, Kathleen
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009511/
https://www.ncbi.nlm.nih.gov/pubmed/20122212
http://dx.doi.org/10.1186/1471-2105-11-S1-S39

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