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An automated framework for understanding structural variations in the binding grooves of MHC class II molecules
BACKGROUND: MHC/HLA class II molecules are important components of the immune system and play a critical role in processes such as phagocytosis. Understanding peptide recognition properties of the hundreds of MHC class II alleles is essential to appreciate determinants of antigenicity and ultimately...
Autores principales: | Yeturu, Kalidas, Utriainen, Tapani, Kemp, Graham JL, Chandra, Nagasuma |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009528/ https://www.ncbi.nlm.nih.gov/pubmed/20122230 http://dx.doi.org/10.1186/1471-2105-11-S1-S55 |
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