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An integrative modular approach to systematically predict gene-phenotype associations
BACKGROUND: Complex human diseases are often caused by multiple mutations, each of which contributes only a minor effect to the disease phenotype. To study the basis for these complex phenotypes, we developed a network-based approach to identify coexpression modules specifically activated in particu...
Autores principales: | Mehan, Michael R, Nunez-Iglesias, Juan, Dai, Chao, Waterman, Michael S, Zhou, Xianghong Jasmine |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009536/ https://www.ncbi.nlm.nih.gov/pubmed/20122238 http://dx.doi.org/10.1186/1471-2105-11-S1-S62 |
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