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Structural Basis for Apoptosis Inhibition by Epstein-Barr Virus BHRF1
Epstein-Barr virus (EBV) is associated with human malignancies, especially those affecting the B cell compartment such as Burkitt lymphoma. The virally encoded homolog of the mammalian pro-survival protein Bcl-2, BHRF1 contributes to viral infectivity and lymphomagenesis. In addition to the pro-apop...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009601/ https://www.ncbi.nlm.nih.gov/pubmed/21203485 http://dx.doi.org/10.1371/journal.ppat.1001236 |