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Development of an In Vivo RNAi Protocol to Investigate Gene Function in the Filarial Nematode, Brugia malayi

Our ability to control diseases caused by parasitic nematodes is constrained by a limited portfolio of effective drugs and a paucity of robust tools to investigate parasitic nematode biology. RNA interference (RNAi) is a reverse-genetics tool with great potential to identify novel drug targets and i...

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Detalles Bibliográficos
Autores principales: Song, Chuanzhe, Gallup, Jack M., Day, Tim A., Bartholomay, Lyric C., Kimber, Michael J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009605/
https://www.ncbi.nlm.nih.gov/pubmed/21203489
http://dx.doi.org/10.1371/journal.ppat.1001239