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Corticosteroid effects on ventilator-induced diaphragm dysfunction in anesthetized rats depend on the dose administered

BACKGROUND: High dose of corticosteroids has been previously shown to protect against controlled mechanical ventilation (CMV)-induced diaphragmatic dysfunction while inhibiting calpain activation. Because literature suggests that the calpain inhibiting effect of corticosteroid depends on the dose ad...

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Detalles Bibliográficos
Autores principales: Maes, Karen, Agten, Anouk, Smuder, Ashley, Powers, Scott K, Decramer, Marc, Gayan-Ramirez, Ghislaine
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009634/
https://www.ncbi.nlm.nih.gov/pubmed/21156051
http://dx.doi.org/10.1186/1465-9921-11-178