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Cleavage of Phosphorothioated DNA and Methylated DNA by the Type IV Restriction Endonuclease ScoMcrA

Many taxonomically diverse prokaryotes enzymatically modify their DNA by replacing a non-bridging oxygen with a sulfur atom at specific sequences. The biological implications of this DNA S-modification (phosphorothioation) were unknown. We observed that simultaneous expression of the dndA-E gene clu...

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Detalles Bibliográficos
Autores principales:	Liu, Guang, Ou, Hong-Yu, Wang, Tao, Li, Li, Tan, Huarong, Zhou, Xiufen, Rajakumar, Kumar, Deng, Zixin, He, Xinyi
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009677/ https://www.ncbi.nlm.nih.gov/pubmed/21203499 http://dx.doi.org/10.1371/journal.pgen.1001253

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