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Human homolog of Drosophila Hairy and enhancer of split 1, Hes1, negatively regulates δ-catenin (CTNND2) expression in cooperation with E2F1 in prostate cancer

BACKGROUND: Neuronal synaptic junction protein δ-catenin (CTNND2) is often overexpressed in prostatic adenocarcinomas but the mechanisms of its activation are unknown. To address this question, we studied the hypothesis that Hes1, human homolog of Drosophila Hairy and enhancer of split (Hes) 1, is a...

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Detalles Bibliográficos
Autores principales:	Lu, Jian-Ping, Zhang, Jiao, Kim, Kwonseop, Case, Thomas C, Matusik, Robert J, Chen, Yan-hua, Wolfe, Michael, Nopparat, Jongdee, Lu, Qun
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009707/ https://www.ncbi.nlm.nih.gov/pubmed/21106062 http://dx.doi.org/10.1186/1476-4598-9-304

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