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Loss of Caveolin-1 Accelerates Neurodegeneration and Aging

BACKGROUND: The aged brain exhibits a loss in gray matter and a decrease in spines and synaptic densities that may represent a sequela for neurodegenerative diseases such as Alzheimer's. Membrane/lipid rafts (MLR), discrete regions of the plasmalemma enriched in cholesterol, glycosphingolipids,...

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Detalles Bibliográficos
Autores principales:	Head, Brian P., Peart, Jason N., Panneerselvam, Mathivadhani, Yokoyama, Takaakira, Pearn, Matthew L., Niesman, Ingrid R., Bonds, Jacqueline A., Schilling, Jan M., Miyanohara, Atsushi, Headrick, John, Ali, Sameh S., Roth, David M., Patel, Piyush M., Patel, Hemal H.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009734/ https://www.ncbi.nlm.nih.gov/pubmed/21203469 http://dx.doi.org/10.1371/journal.pone.0015697

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