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Structural Basis of the Association of HIV-1 Matrix Protein with DNA

HIV-1 matrix (MA) is a multifunctional protein that is synthesized as a polyprotein that is cleaved by protease during viral maturation. MA contains a cluster of basic residues whose role is controversial. Proposed functions include membrane anchoring, facilitating viral assembly, and directing nucl...

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Detalles Bibliográficos
Autores principales: Cai, Mengli, Huang, Ying, Craigie, Robert, Clore, G. Marius
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009736/
https://www.ncbi.nlm.nih.gov/pubmed/21203471
http://dx.doi.org/10.1371/journal.pone.0015675