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Role of endogenous and exogenous female sex hormones in arthritis and osteoporosis development in B10.Q-ncf1(*/* )mice with collagen-induced chronic arthritis
BACKGROUND: Collagen-induced arthritis (CIA) is an often-used murine model for human rheumatoid arthritis (RA). Earlier studies have shown potent anti-arthritic effects with the female sex hormone estradiol and the selective estrogen receptor modulator (SERM) raloxifene in CIA in DBA/1-mice. B10.Q-n...
Autores principales: | Jochems, Caroline, Islander, Ulrika, Erlandsson, Malin, Engdahl, Cecilia, Lagerquist, Marie, Gjertsson, Inger, Ohlsson, Claes, Holmdahl, Rikard, Carlsten, Hans |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009959/ https://www.ncbi.nlm.nih.gov/pubmed/21159208 http://dx.doi.org/10.1186/1471-2474-11-284 |
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