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Nicotine up-regulates α4β2 nicotinic receptors and ER exit sites via stoichiometry-dependent chaperoning
The up-regulation of α4β2* nicotinic acetylcholine receptors (nAChRs) by chronic nicotine is a cell-delimited process and may be necessary and sufficient for the initial events of nicotine dependence. Clinical literature documents an inverse relationship between a person’s history of tobacco use and...
Autores principales: | Srinivasan, Rahul, Pantoja, Rigo, Moss, Fraser J., Mackey, Elisha D.W., Son, Cagdas D., Miwa, Julie, Lester, Henry A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3010053/ https://www.ncbi.nlm.nih.gov/pubmed/21187334 http://dx.doi.org/10.1085/jgp.201010532 |
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