Single-cell quantification of IL-2 response by effector and regulatory T cells reveals critical plasticity in immune response

Understanding how the immune system decides between tolerance and activation by antigens requires addressing cytokine regulation as a highly dynamic process. We quantified the dynamics of interleukin-2 (IL-2) signaling in a population of T cells during an immune response by combining in silico model...

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Detalles Bibliográficos
Autores principales: Feinerman, Ofer, Jentsch, Garrit, Tkach, Karen E, Coward, Jesse W, Hathorn, Matthew M, Sneddon, Michael W, Emonet, Thierry, Smith, Kendall A, Altan-Bonnet, Grégoire
Formato: Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3010113/
https://www.ncbi.nlm.nih.gov/pubmed/21119631
http://dx.doi.org/10.1038/msb.2010.90

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3010113/
https://www.ncbi.nlm.nih.gov/pubmed/21119631
http://dx.doi.org/10.1038/msb.2010.90

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