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Vimentin is a novel AKT1 target mediating motility and invasion
The PI3K/AKT signaling pathway is aberrant in a wide variety of cancers. Downstream effectors of AKT are involved in survival, growth, and metabolic-related pathways. In contrast, contradictory data relating to AKT effects on cell motility and invasion, crucial pro-metastatic processes, have been re...
Autores principales: | Zhu, Quan-Sheng, Rosenblatt, Kevin, Huang, Kai-Lieh, Lahat, Guy, Brobey, Reynolds, Bolshakov, Svetlana, Nguyen, Theresa, Ding, Zhiyong, Belousov, Roman, Bill, Katelynn, Luo, Xuemei, Lazar, Alexander, Dicker, Adam, Mills, Gordon B., Hung, Mien-Chie, Lev, Dina |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3010301/ https://www.ncbi.nlm.nih.gov/pubmed/20856200 http://dx.doi.org/10.1038/onc.2010.421 |
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