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Knockdown of splicing factor SRp20 causes apoptosis in ovarian cancer cells and its expression is associated with malignancy of epithelial ovarian cancer

Our previous study revealed that two splicing factors, polypyrimidine tract-binding protein (PTB) and SRp20, were up-regulated in epithelial ovarian cancer (EOC) and knockdown of PTB expression inhibited ovarian tumor cell growth and transformation properties. In this report, we show that knockdown...

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Detalles Bibliográficos
Autores principales: He, Xiaolong, Arslan, Ahmet Dirim, Pool, Mark D., Ho, Tsui-Ting, Darcy, Kathleen M., Coon, John S., Beck, William T.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3010329/
https://www.ncbi.nlm.nih.gov/pubmed/20856201
http://dx.doi.org/10.1038/onc.2010.426