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Inflammatory Cytokine Inhibition with Combination Daclizumab and Infliximab for Steroid Refractory Acute Graft-Versus-Host Disease

Treatment options for steroid-refractory GVHD (SR-GVHD) are unsatisfactory and prognosis is poor. Inflammatory cytokines IL-2 and TNF-α are important mediators of GVHD, and may be critical targets for therapy. We retrospectively reviewed our experience using combination anti-cytokine therapy of dacl...

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Detalles Bibliográficos
Autores principales: Rager, Alison, Frey, Noelle, Goldstein, Steven C, Reshef, Ran, Hexner, Elizabeth O, Loren, Alison, Luger, Selina M, Perl, Alexander, Tsai, Donald, Davis, Jennifer, Vozniak, Michael, Smith, Jacqueline, Stadtmauer, Edward A, Porter, David L
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3010487/
https://www.ncbi.nlm.nih.gov/pubmed/20498647
http://dx.doi.org/10.1038/bmt.2010.117