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Synthesis of Peptides from α- and β-Tubulin Containing Glutamic Acid Side-Chain Linked Oligo-Glu with Defined Length

Side-chain oligo- and polyglutamylation represents an important posttranslational modification in tubulin physiology. The particular number of glutamate units is related to specific regulatory functions. In this work, we present a method for the synthesis of building blocks for the Fmoc synthesis of...

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Detalles Bibliográficos
Autores principales: Tegge, Werner, Bonafe, Carlos F. S., Teichmann, Aileen, Erck, Christian
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3010639/
https://www.ncbi.nlm.nih.gov/pubmed/21197436
http://dx.doi.org/10.1155/2010/189396