ERG oncoprotein expression in prostate cancer: clonal progression of ERG-positive tumor cells and potential for ERG-based stratification

Gene fusions prevalent in prostate cancer (CaP) lead to the elevated expression of the ERG proto-oncogene. ERG activation present in 50–70% of prostate tumors underscores one of the most common oncogenic alterations in CaP. Despite numerous reports of gene fusions and mRNA expression, ERG oncoprotei...

Descripción completa

Detalles Bibliográficos
Autores principales: Furusato, B, Tan, S-H, Young, D, Dobi, A, Sun, C, Mohamed, A A, Thangapazham, R, Chen, Y, McMaster, G, Sreenath, T, Petrovics, G, McLeod, D G, Srivastava, S, Sesterhenn, I A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3010744/
https://www.ncbi.nlm.nih.gov/pubmed/20585344
http://dx.doi.org/10.1038/pcan.2010.23

Ejemplares similares

Ejemplares similares