Aldose Reductase Inhibition Prevents Metaplasia of Airway Epithelial Cells

BACKGROUND: Goblet cell metaplasia that causes mucus hypersecretion and obstruction in the airway lumen could be life threatening in asthma and chronic obstructive pulmonary disease patients. Inflammatory cytokines such as IL-13 mediate the transformation of airway ciliary epithelial cells to mucin-...

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Detalles Bibliográficos
Autores principales: Yadav, Umesh C. S., Aguilera-Aguirre, Leopoldo, Ramana, Kota V., Boldogh, Istvan, Srivastava, Satish K.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3010981/
https://www.ncbi.nlm.nih.gov/pubmed/21203431
http://dx.doi.org/10.1371/journal.pone.0014440

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3010981/
https://www.ncbi.nlm.nih.gov/pubmed/21203431
http://dx.doi.org/10.1371/journal.pone.0014440

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