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Molecular Basis of Differential B-Pentamer Stability of Shiga Toxins 1 and 2
Escherichia coli strain O157:H7 is a major cause of food poisoning that can result in severe diarrhea and, in some cases, renal failure. The pathogenesis of E. coli O157:H7 is in large part due to the production of Shiga toxin (Stx), an AB(5) toxin that consists of a ribosomal RNA-cleaving A-subunit...
Autores principales: | Conrady, Deborah G., Flagler, Michael J., Friedmann, David R., Vander Wielen, Bradley D., Kovall, Rhett A., Weiss, Alison A., Herr, Andrew B. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3010993/ https://www.ncbi.nlm.nih.gov/pubmed/21203383 http://dx.doi.org/10.1371/journal.pone.0015153 |
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