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Role of Sphingomyelin Synthase in Controlling the Antimicrobial Activity of Neutrophils against Cryptococcus neoformans

The key host cellular pathway(s) necessary to control the infection caused by inhalation of the environmental fungal pathogen Cryptococcus neoformans are still largely unknown. Here we have identified that the sphingolipid pathway in neutrophils is required for them to exert their killing activity o...

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Detalles Bibliográficos
Autores principales: Qureshi, Asfia, Subathra, Marimuthu, Grey, Angus, Schey, Kevin, Del Poeta, Maurizio, Luberto, Chiara
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3011003/
https://www.ncbi.nlm.nih.gov/pubmed/21203393
http://dx.doi.org/10.1371/journal.pone.0015587