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Mitochondrial Dysfunction and Apoptosis in Cumulus Cells of Type I Diabetic Mice

Impaired oocyte quality has been demonstrated in diabetic mice; however, the potential pathways by which maternal diabetes exerts its effects on the oocyte are poorly understood. Cumulus cells are in direct contact with the oocyte via gap junctions and provide essential nutrients to support oocyte d...

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Detalles Bibliográficos
Autores principales: Wang, Qiang, Frolova, Antonina I., Purcell, Scott, Adastra, Katie, Schoeller, Erica, Chi, Maggie M., Schedl, Tim, Moley, Kelle H.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3011018/
https://www.ncbi.nlm.nih.gov/pubmed/21209947
http://dx.doi.org/10.1371/journal.pone.0015901

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