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IMMUNOGLOBULIN PATTERNS IN SCHIZOPHRENIC PATIENTS1
Immunoglobulins G, M and A were estimated in serum and cerebrospinal fluid (CSF) of 30 schizophrenics, 20 neurological controls and 20 surgical controls. Significant increased levels of serum Ig A and M were detected in schizophrenics. An association was observed between increasing levels of serum I...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications
1984
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3011242/ https://www.ncbi.nlm.nih.gov/pubmed/21965989 |
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author | Tiwari, S.G. Lal, Narottam Trivedi, J.K. Sayeed, J. Bahauguna, L.M. |
author_facet | Tiwari, S.G. Lal, Narottam Trivedi, J.K. Sayeed, J. Bahauguna, L.M. |
author_sort | Tiwari, S.G. |
collection | PubMed |
description | Immunoglobulins G, M and A were estimated in serum and cerebrospinal fluid (CSF) of 30 schizophrenics, 20 neurological controls and 20 surgical controls. Significant increased levels of serum Ig A and M were detected in schizophrenics. An association was observed between increasing levels of serum IgA and IgM with the duration of disease and the number of episodes. CSF IgG/TP% was also significantly increased with the severity of the disease. On the basis of viral aetiology of schizophrenia it can be concluded that the increase in immunoglobulins synthesis might be due to the persistent antigenic stimulation. |
format | Text |
id | pubmed-3011242 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1984 |
publisher | Medknow Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-30112422011-10-02 IMMUNOGLOBULIN PATTERNS IN SCHIZOPHRENIC PATIENTS1 Tiwari, S.G. Lal, Narottam Trivedi, J.K. Sayeed, J. Bahauguna, L.M. Indian J Psychiatry Original Article Immunoglobulins G, M and A were estimated in serum and cerebrospinal fluid (CSF) of 30 schizophrenics, 20 neurological controls and 20 surgical controls. Significant increased levels of serum Ig A and M were detected in schizophrenics. An association was observed between increasing levels of serum IgA and IgM with the duration of disease and the number of episodes. CSF IgG/TP% was also significantly increased with the severity of the disease. On the basis of viral aetiology of schizophrenia it can be concluded that the increase in immunoglobulins synthesis might be due to the persistent antigenic stimulation. Medknow Publications 1984 /pmc/articles/PMC3011242/ /pubmed/21965989 Text en Copyright: © Indian Journal of Psychiatry http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Tiwari, S.G. Lal, Narottam Trivedi, J.K. Sayeed, J. Bahauguna, L.M. IMMUNOGLOBULIN PATTERNS IN SCHIZOPHRENIC PATIENTS1 |
title | IMMUNOGLOBULIN PATTERNS IN SCHIZOPHRENIC PATIENTS1 |
title_full | IMMUNOGLOBULIN PATTERNS IN SCHIZOPHRENIC PATIENTS1 |
title_fullStr | IMMUNOGLOBULIN PATTERNS IN SCHIZOPHRENIC PATIENTS1 |
title_full_unstemmed | IMMUNOGLOBULIN PATTERNS IN SCHIZOPHRENIC PATIENTS1 |
title_short | IMMUNOGLOBULIN PATTERNS IN SCHIZOPHRENIC PATIENTS1 |
title_sort | immunoglobulin patterns in schizophrenic patients1 |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3011242/ https://www.ncbi.nlm.nih.gov/pubmed/21965989 |
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