(1R,4aS,10aR)-1,4a-Dimethyl-N-[(morpholin-4-yl)carbothio­yl]-7-(propan-2-yl)-1,2,3,4,4a,9,10,10a-octa­hydro­phenanthrene-1-carboxamide

In the title compound, C(25)H(36)N(2)O(2)S, the cyclo­hexane and morpholine rings adopt chair conformations. The cyclo­hexene and cyclo­hexane rings form a trans ring junction with the two methyl groups in axial positions. The N—H and C=O bonds in the urea group are anti to each other. The crystal s...

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Detalles Bibliográficos
Autores principales: Rao, Xiao-Ping, Wu, Yong, Song, Zhan-Qian, Shang, Shi-Bin
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3011422/
https://www.ncbi.nlm.nih.gov/pubmed/21589388
http://dx.doi.org/10.1107/S1600536810044569
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author Rao, Xiao-Ping
Wu, Yong
Song, Zhan-Qian
Shang, Shi-Bin
author_facet Rao, Xiao-Ping
Wu, Yong
Song, Zhan-Qian
Shang, Shi-Bin
author_sort Rao, Xiao-Ping
collection PubMed
description In the title compound, C(25)H(36)N(2)O(2)S, the cyclo­hexane and morpholine rings adopt chair conformations. The cyclo­hexene and cyclo­hexane rings form a trans ring junction with the two methyl groups in axial positions. The N—H and C=O bonds in the urea group are anti to each other. The crystal structure is stabilized by inter­molecular N—H⋯O hydrogen bonds.
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spelling pubmed-30114222010-12-30 (1R,4aS,10aR)-1,4a-Dimethyl-N-[(morpholin-4-yl)carbothio­yl]-7-(propan-2-yl)-1,2,3,4,4a,9,10,10a-octa­hydro­phenanthrene-1-carboxamide Rao, Xiao-Ping Wu, Yong Song, Zhan-Qian Shang, Shi-Bin Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(25)H(36)N(2)O(2)S, the cyclo­hexane and morpholine rings adopt chair conformations. The cyclo­hexene and cyclo­hexane rings form a trans ring junction with the two methyl groups in axial positions. The N—H and C=O bonds in the urea group are anti to each other. The crystal structure is stabilized by inter­molecular N—H⋯O hydrogen bonds. International Union of Crystallography 2010-11-06 /pmc/articles/PMC3011422/ /pubmed/21589388 http://dx.doi.org/10.1107/S1600536810044569 Text en © Rao et al. 2010 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Rao, Xiao-Ping
Wu, Yong
Song, Zhan-Qian
Shang, Shi-Bin
(1R,4aS,10aR)-1,4a-Dimethyl-N-[(morpholin-4-yl)carbothio­yl]-7-(propan-2-yl)-1,2,3,4,4a,9,10,10a-octa­hydro­phenanthrene-1-carboxamide
title (1R,4aS,10aR)-1,4a-Dimethyl-N-[(morpholin-4-yl)carbothio­yl]-7-(propan-2-yl)-1,2,3,4,4a,9,10,10a-octa­hydro­phenanthrene-1-carboxamide
title_full (1R,4aS,10aR)-1,4a-Dimethyl-N-[(morpholin-4-yl)carbothio­yl]-7-(propan-2-yl)-1,2,3,4,4a,9,10,10a-octa­hydro­phenanthrene-1-carboxamide
title_fullStr (1R,4aS,10aR)-1,4a-Dimethyl-N-[(morpholin-4-yl)carbothio­yl]-7-(propan-2-yl)-1,2,3,4,4a,9,10,10a-octa­hydro­phenanthrene-1-carboxamide
title_full_unstemmed (1R,4aS,10aR)-1,4a-Dimethyl-N-[(morpholin-4-yl)carbothio­yl]-7-(propan-2-yl)-1,2,3,4,4a,9,10,10a-octa­hydro­phenanthrene-1-carboxamide
title_short (1R,4aS,10aR)-1,4a-Dimethyl-N-[(morpholin-4-yl)carbothio­yl]-7-(propan-2-yl)-1,2,3,4,4a,9,10,10a-octa­hydro­phenanthrene-1-carboxamide
title_sort (1r,4as,10ar)-1,4a-dimethyl-n-[(morpholin-4-yl)carbothio­yl]-7-(propan-2-yl)-1,2,3,4,4a,9,10,10a-octa­hydro­phenanthrene-1-carboxamide
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3011422/
https://www.ncbi.nlm.nih.gov/pubmed/21589388
http://dx.doi.org/10.1107/S1600536810044569
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