(2R,4R)-1-(tert-But­oxy­carbon­yl)-4-meth­oxy­pyrrolidine-2-carb­oxy­lic acid

In the title compound, C(11)H(19)NO(5), the five-membered pyrrolidine ring adopts an envelope conformation. The dihedral angles between the carboxyl group plane, the pyrrolidine ring and the meth­oxy group are 59.50 (3) and 62.02 (1)°, respectively. In the crystal, inter­molecular O—H⋯O hydrogen bon...

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Detalles Bibliográficos
Autores principales: Yuan, Jing, Cai, Zhi-Qiang, Huang, Chang-Jiang, Xu, Wei-Ren
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3011444/
https://www.ncbi.nlm.nih.gov/pubmed/21589542
http://dx.doi.org/10.1107/S1600536810047707
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author Yuan, Jing
Cai, Zhi-Qiang
Huang, Chang-Jiang
Xu, Wei-Ren
author_facet Yuan, Jing
Cai, Zhi-Qiang
Huang, Chang-Jiang
Xu, Wei-Ren
author_sort Yuan, Jing
collection PubMed
description In the title compound, C(11)H(19)NO(5), the five-membered pyrrolidine ring adopts an envelope conformation. The dihedral angles between the carboxyl group plane, the pyrrolidine ring and the meth­oxy group are 59.50 (3) and 62.02 (1)°, respectively. In the crystal, inter­molecular O—H⋯O hydrogen bonds link the mol­ecules into chains along [100]. The absolute configuration is assigned in accord with that of (2R,4R)-1-(tert-but­oxy­carbon­yl)-4-hy­droxy­pyrrolidine-2-carb­oxy­lic acid, which was the starting material in the synthesis.
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spelling pubmed-30114442010-12-30 (2R,4R)-1-(tert-But­oxy­carbon­yl)-4-meth­oxy­pyrrolidine-2-carb­oxy­lic acid Yuan, Jing Cai, Zhi-Qiang Huang, Chang-Jiang Xu, Wei-Ren Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(11)H(19)NO(5), the five-membered pyrrolidine ring adopts an envelope conformation. The dihedral angles between the carboxyl group plane, the pyrrolidine ring and the meth­oxy group are 59.50 (3) and 62.02 (1)°, respectively. In the crystal, inter­molecular O—H⋯O hydrogen bonds link the mol­ecules into chains along [100]. The absolute configuration is assigned in accord with that of (2R,4R)-1-(tert-but­oxy­carbon­yl)-4-hy­droxy­pyrrolidine-2-carb­oxy­lic acid, which was the starting material in the synthesis. International Union of Crystallography 2010-11-20 /pmc/articles/PMC3011444/ /pubmed/21589542 http://dx.doi.org/10.1107/S1600536810047707 Text en © Yuan et al. 2010 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Yuan, Jing
Cai, Zhi-Qiang
Huang, Chang-Jiang
Xu, Wei-Ren
(2R,4R)-1-(tert-But­oxy­carbon­yl)-4-meth­oxy­pyrrolidine-2-carb­oxy­lic acid
title (2R,4R)-1-(tert-But­oxy­carbon­yl)-4-meth­oxy­pyrrolidine-2-carb­oxy­lic acid
title_full (2R,4R)-1-(tert-But­oxy­carbon­yl)-4-meth­oxy­pyrrolidine-2-carb­oxy­lic acid
title_fullStr (2R,4R)-1-(tert-But­oxy­carbon­yl)-4-meth­oxy­pyrrolidine-2-carb­oxy­lic acid
title_full_unstemmed (2R,4R)-1-(tert-But­oxy­carbon­yl)-4-meth­oxy­pyrrolidine-2-carb­oxy­lic acid
title_short (2R,4R)-1-(tert-But­oxy­carbon­yl)-4-meth­oxy­pyrrolidine-2-carb­oxy­lic acid
title_sort (2r,4r)-1-(tert-but­oxy­carbon­yl)-4-meth­oxy­pyrrolidine-2-carb­oxy­lic acid
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3011444/
https://www.ncbi.nlm.nih.gov/pubmed/21589542
http://dx.doi.org/10.1107/S1600536810047707
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AT caizhiqiang 2r4r1tertbutoxycarbonyl4methoxypyrrolidine2carboxylicacid
AT huangchangjiang 2r4r1tertbutoxycarbonyl4methoxypyrrolidine2carboxylicacid
AT xuweiren 2r4r1tertbutoxycarbonyl4methoxypyrrolidine2carboxylicacid

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