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rac-2-[2-(4-Fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-N-phenylpentanamide
The title compound, C(26)H(24)FNO(3), is a critical intermediate of a selective and competitive inhibitor of the enzyme 3-hydroxy-3-methylglutaryl-coenzyme A (HMG–CoA) reductase. Intermolecular N—H⋯O hydrogen bonding generates a chain along [give direction] that is the dominant interaction in t...
Autores principales: | Zhou, Feng-yan, Huang, Jian-ying |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3011484/ https://www.ncbi.nlm.nih.gov/pubmed/21589464 http://dx.doi.org/10.1107/S1600536810046271 |
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