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1-{[5-(4-Chlorophenyl)-1-(4-fluorophenyl)-1H-pyrazol-3-yl]carbonyl]}piperidin-4-one
In the title compound, C(21)H(17)ClFN(3)O(2), the 1H-pyrazole ring makes dihedral angles of 36.73 (7), 18.73 (7) and 60.88 (8)°, respectively, with the mean planes of the chlorophenyl, 4-oxopiperidine and fluorophenyl rings. The molecular structure is stabilized by an intramolecular C—H⋯N hydro...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3011612/ https://www.ncbi.nlm.nih.gov/pubmed/21589523 http://dx.doi.org/10.1107/S1600536810047215 |
Sumario: | In the title compound, C(21)H(17)ClFN(3)O(2), the 1H-pyrazole ring makes dihedral angles of 36.73 (7), 18.73 (7) and 60.88 (8)°, respectively, with the mean planes of the chlorophenyl, 4-oxopiperidine and fluorophenyl rings. The molecular structure is stabilized by an intramolecular C—H⋯N hydrogen bond, which forms an S(6) ring motif. In the crystal, intermolecular C—H⋯O hydrogen bonds link molecules into chains along [101]. In addition, intermolecular C—H⋯F hydrogen bonds with an R (2) (1)(7) ring motif connect neighbouring chains into layers parallel to the ac plane. |
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