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3-Ethyl 2-methyl 8-bromo-2-phenyl-1,2,3,3a,4,9b-hexa­hydro­chromeno[4,3-b]pyrrole-2,3-dicarboxyl­ate

The title compound, C(22)H(22)BrNO(5), was synthesized by the intra­molecular cyclo­addition reaction of (E)-ethyl 4-(4-bromo-2-formyl­phen­oxy)but-2-enoate and methyl 2-amino-2-phenyl­acetate. The pyrrolidine and 3,4-dihydro-2H-pyran rings exhibit envelope conformations. The two benzene rings are t...

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Detalles Bibliográficos
Autor principal: He, Long
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3011766/
https://www.ncbi.nlm.nih.gov/pubmed/21589384
http://dx.doi.org/10.1107/S1600536810044491
Descripción
Sumario:The title compound, C(22)H(22)BrNO(5), was synthesized by the intra­molecular cyclo­addition reaction of (E)-ethyl 4-(4-bromo-2-formyl­phen­oxy)but-2-enoate and methyl 2-amino-2-phenyl­acetate. The pyrrolidine and 3,4-dihydro-2H-pyran rings exhibit envelope conformations. The two benzene rings are twisted to each other at a dihedral angle of 59.36 (18)°. The eth­oxy group of the ester unit is disordered over two sites with an occupancy ratio of 0.503 (11):0.497 (11). Weak inter­molecular C—H⋯O hydrogen bonding is present in the crystal structure.