Birt-Hogg-Dubé renal tumors are genetically distinct from other renal neoplasias and are associated with up-regulation of mitochondrial gene expression

BACKGROUND: Germline mutations in the folliculin (FLCN) gene are associated with the development of Birt-Hogg-Dubé syndrome (BHDS), a disease characterized by papular skin lesions, a high occurrence of spontaneous pneumothorax, and the development of renal neoplasias. The majority of renal tumors th...

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Detalles Bibliográficos
Autores principales: Klomp, Jeff A, Petillo, David, Niemi, Natalie M, Dykema, Karl J, Chen, Jindong, Yang, Ximing J, Sääf, Annika, Zickert, Peter, Aly, Markus, Bergerheim, Ulf, Nordenskjöld, Magnus, Gad, Sophie, Giraud, Sophie, Denoux, Yves, Yonneau, Laurent, Méjean, Arnaud, Vasiliu, Viorel, Richard, Stéphane, MacKeigan, Jeffrey P, Teh, Bin T, Furge, Kyle A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012009/
https://www.ncbi.nlm.nih.gov/pubmed/21162720
http://dx.doi.org/10.1186/1755-8794-3-59

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