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Simvastatin impairs murine melanoma growth

BACKGROUND: Statins induces cell cycle arrest, apoptosis, reduction of angiogenic factors, inhibition of the endothelial growth factor, impairing tissue adhesion and attenuation of the resistance mechanisms. The aim of this study was evaluate the anti-tumoral activity of simvastatin in a B16F10 mela...

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Detalles Bibliográficos
Autores principales:	Favero, Giovani M, F Otuki, Michel, Oliveira, Karen A, Bohatch, Milton S, Borelli, Primavera, Barros, Francisco E, Maria, Durvanei A, Fernandes, Daniel, Bydlowski, Sergio P
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012033/ https://www.ncbi.nlm.nih.gov/pubmed/21162733 http://dx.doi.org/10.1186/1476-511X-9-142

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