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Different Patterns of Evolution in the Centromeric and Telomeric Regions of Group A and B Haplotypes of the Human Killer Cell Ig-Like Receptor Locus

The fast evolving human KIR gene family encodes variable lymphocyte receptors specific for polymorphic HLA class I determinants. Nucleotide sequences for 24 representative human KIR haplotypes were determined. With three previously defined haplotypes, this gave a set of 12 group A and 15 group B hap...

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Detalles Bibliográficos
Autores principales: Pyo, Chul-Woo, Guethlein, Lisbeth A., Vu, Quyen, Wang, Ruihan, Abi-Rached, Laurent, Norman, Paul J., Marsh, Steven G. E., Miller, Jeffrey S., Parham, Peter, Geraghty, Daniel E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012066/
https://www.ncbi.nlm.nih.gov/pubmed/21206914
http://dx.doi.org/10.1371/journal.pone.0015115