Oral Methylthioadenosine Administration Attenuates Fibrosis and Chronic Liver Disease Progression in Mdr2−/− Mice

BACKGROUND: Inflammation and fibrogenesis are directly related to chronic liver disease progression, including hepatocellular carcinoma (HCC) development. Currently there are few therapeutic options available to inhibit liver fibrosis. We have evaluated the hepatoprotective and anti-fibrotic potenti...

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Detalles Bibliográficos
Autores principales: Latasa, M. Ujue, Gil-Puig, Carmen, Fernández-Barrena, Maite G., Rodríguez-Ortigosa, Carlos M., Banales, Jesús M., Urtasun, Raquel, Goñi, Saioa, Méndez, Miriam, Arcelus, Sara, Juanarena, Nerea, Recio, Juan A., Lotersztajn, Sophie, Prieto, Jesús, Berasain, Carmen, Corrales, Fernando J., Lecanda, Jon, Ávila, Matías A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012093/
https://www.ncbi.nlm.nih.gov/pubmed/21209952
http://dx.doi.org/10.1371/journal.pone.0015690

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