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Understanding the Sequence-Dependence of DNA Groove Dimensions: Implications for DNA Interactions

BACKGROUND: The B-DNA major and minor groove dimensions are crucial for DNA-protein interactions. It has long been thought that the groove dimensions depend on the DNA sequence, however this relationship has remained elusive. Here, our aim is to elucidate how the DNA sequence intrinsically shapes th...

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Detalles Bibliográficos
Autores principales: Oguey, Christophe, Foloppe, Nicolas, Hartmann, Brigitte
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012109/
https://www.ncbi.nlm.nih.gov/pubmed/21209967
http://dx.doi.org/10.1371/journal.pone.0015931

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