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Understanding the Sequence-Dependence of DNA Groove Dimensions: Implications for DNA Interactions
BACKGROUND: The B-DNA major and minor groove dimensions are crucial for DNA-protein interactions. It has long been thought that the groove dimensions depend on the DNA sequence, however this relationship has remained elusive. Here, our aim is to elucidate how the DNA sequence intrinsically shapes th...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012109/ https://www.ncbi.nlm.nih.gov/pubmed/21209967 http://dx.doi.org/10.1371/journal.pone.0015931 |