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Characterization of Neuraminidases from the Highly Pathogenic Avian H5N1 and 2009 Pandemic H1N1 Influenza A Viruses

To study the precise role of the neuraminidase (NA), and its stalk region in particular, in the assembly, release, and entry of influenza virus, we deleted the 20-aa stalk segment from 2009 pandemic H1N1 NA (09N1) and inserted this segment, now designated 09s60, into the stalk region of a highly pat...

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Detalles Bibliográficos
Autores principales: Wu, Jia, Zhang, Fengwei, Wang, Maorong, Xu, Chunqiong, Song, Jingdong, Zhou, Jianfang, Lin, Xiaojing, Zhang, Yonghui, Wu, Xiaobing, Tan, Wenjie, Lu, Jian, Zhao, Honglan, Gao, Jimin, Zhao, Ping, Lu, Jianxin, Wang, Yue
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012118/
https://www.ncbi.nlm.nih.gov/pubmed/21209916
http://dx.doi.org/10.1371/journal.pone.0015825