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Mitochondrial Biogenesis and Peroxisome Proliferator–Activated Receptor-γ Coactivator-1α (PGC-1α) Deacetylation by Physical Activity: Intact Adipocytokine Signaling Is Required
OBJECTIVE: Transcriptional peroxisome proliferator–activated receptor-γ coactivator-1α (PGC-1α) plays a key role in mitochondrial biogenesis and energy metabolism and is suggested to be involved in the exercise-induced increase in mitochondrial content. PGC-1α activity is regulated by posttranslatio...
Autores principales: | Li, Ling, Pan, Ruping, Li, Rong, Niemann, Bernd, Aurich, Anne-Cathleen, Chen, Ying, Rohrbach, Susanne |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012167/ https://www.ncbi.nlm.nih.gov/pubmed/20929977 http://dx.doi.org/10.2337/db10-0331 |
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