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Production of Functional Glucagon-Secreting α-Cells From Human Embryonic Stem Cells

OBJECTIVE: Differentiation of human embryonic stem (hES) cells to fully developed cell types holds great therapeutic promise. Despite significant progress, the conversion of hES cells to stable, fully differentiated endocrine cells that exhibit physiologically regulated hormone secretion has not yet...

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Detalles Bibliográficos
Autores principales:	Rezania, Alireza, Riedel, Michael J., Wideman, Rhonda D., Karanu, Francis, Ao, Ziliang, Warnock, Garth L., Kieffer, Timothy J.
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2011
Materias:	Immunology and Transplantation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012176/ https://www.ncbi.nlm.nih.gov/pubmed/20971966 http://dx.doi.org/10.2337/db10-0573

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